• Air date: 25 Sep '07 16 episodes
      The fourth season of House premiered on September 25, 2007 and ended May 19, 2008. Having previously fired Chase, and with Foreman and Cameron quitting, House starts a competition between forty applicants for the vacant positions. He eventually narrows them down to seven, firing one each episode. In the episode "Games", he fires Amber "Cutthroat Bitch" Volakis, hiring Dr. Chris Taub, Dr. Lawrence Kutner and Dr. Remy "Thirteen" Hadley as his new team. Dr. Foreman rejoins the team after his dismissal from another hospital. Meanwhile, Amber begins a relationship with Wilson. Interrupted by the 2007–2008 Writers Guild of America strike, the number of episodes was reduced to 16 instead of the planned 24. Executive producer Katie Jacobs explained that it was hard for the writers to finish the story arcs started during the season with eight episodes fewer. Season four also introduced seven actors to the cast; in addition to Jacobson, Penn and Wilde, who became regulars, Andy Comeau portrayed Travis Brennan, an epidemiologist; Edi Gathegi played Jeffrey Cole, a geneticist; Carmen Argenziano appeared as Henry Dobson, a former medical school admissions officer; and Anne Dudek portrayed Amber "Cut-throat Bitch" Volakis, an interventional radiologist. Each of the four departed the show after elimination, except for Volakis, who remained recurring until the finale, having started a relationship with Wilson.
  • List of Episodes (16)
    • 1. Alone

      25 Sep '07
      With his diagnostic team gone, House tries to diagnose a young woman who survived an office building collapse. With the condition getting worse, Cuddy puts pressure on House to hire a new team, but instead attempts a differential diagnosis with help from the janitor.
    • 2. The Right Stuff

      02 Oct '07
      House is secretly trying to treat a fighter pilot who is a candidate for NASA's astronaut training program. Her diagnosis will be the test to choose which ones of the 40 applicants are going to take the empty spots in his team.
    • 3. 97 Seconds

      09 Oct '07
      The candidates are now two teams of five women and five men, competing on diagnosing and treating a wheelchair-bound man. Meanwhile House does experiments on himself to test what happens after death, and Foreman, at another hospital, is treating his team in a House-like manner.
    • 4. Guardian Angels

      23 Oct '07
      House finds that some of his own fellowship students will do whatever it takes, when they deal with a woman who believes she can talk to the dead.
    • 5. Mirror Mirror

      30 Oct '07
      House deals with a patient who mirrors the personality of anyone he meets. Meanwhile, Foreman is put in charge of overseeing the fellowship candidates.
    • 6. Whatever It Takes

      06 Nov '07
      Based on practically no information and no medical history about a mystery patient sent by the CIA, House is using some unorthodox methods to diagnose and treat him. Meanwhile the remaining candidates are questioning Foreman's judgment.
    • 7. Ugly

      13 Nov '07
      A film crew and the candidates are following around House distracting him while he is trying to diagnose a teenager who suffers from a heart attack prior to a serious plastic surgery.
    • 8. You Don't Want to Know

      20 Nov '07
      House treats a magician but comes to believe he's faking illness to cover up his own incompetence. Meanwhile, House pits the fellows against each other in his version of an immunity challenge.
    • 9. Games

      27 Nov '07
      Under Cuddy’s pressure to choose his team, House gives the candidates a case of a former punk rock star who is a drug user. Whoever diagnoses the patient is going to have a future as a member of House’s team.
    • 10. It's a Wonderful Lie

      29 Jan '08
      A mother's sudden paralysis during a indoor rock-climbing incident leaves her daughter injured, and House's new team looking for a cure. Meanwhile, House organizes his new recruits' Secret Santa gift exchange... with a few twists of his own.
    • 11. Frozen

      03 Feb '08
      House and his team have to diagnose a case at a distance when a researcher at a South Pole base is taken ill.
    • 12. Don't Ever Change

      05 Feb '08
      House and his team must diagnose a Jewish bride who is taken ill at her wedding. However, House is more interested in analyzing Wilson's relationship with his new girlfriend.
    • 13. No More Mr. Nice Guy

      28 Apr '08
      House copes with a patient whose symptoms conceal a greater problem, but spends much of his time dodging Cuddy's orders to give performance reviews, and fighting with Amber over who gets to spend more time with Wilson.
    • 14. Living the Dream

      05 May '08
      House is convinced one of the actors on his favorite soap opera “Prescription Passion” has a serious medical condition after observing his symptoms on television. House decides to intervene and take matters into his own hands, but both the actor and House's own team dismiss House’s assessment and do not believe there is anything wrong with him.
    • 15. House's Head

      12 May '08
      A bus accident leaves House with serious head trauma and partial amnesia. He comes to believe that a patient on the bus had a life-threatening disease and struggles to recall who it was, and what they had.
    • 16. Wilson's Heart

      19 May '08
      In the aftermath of the bus accident, House struggles with his head injuries and short-term memory loss, and must deal with a concerned Wilson who believes his friend's health may be in danger.