• Air date: 08 Sep '97 51 episodes
      Pinky and Brain are genetically enhanced laboratory mice who reside in a cage in the Acme Labs research facility. Brain is self-centered and scheming; Pinky is good-natured but feebleminded. In each episode, Brain devises a new plan to take over the world, which ultimately ends in failure, usually due to Pinky's idiocy, the impossibility of Brain's plan, Brain's own arrogance, or just circumstances beyond their control.
  • List of Episodes (51)
    • 1. Leave It to Beavers

      08 Sep '97
      Brain enlists the aid of beavers to gain control over the flow of rivers.
    • 2. Cinebrania

      08 Sep '97
      The mice make a series of comedy films and hit the big time.
    • 3. Pinky & The Brain and... Larry

      13 Sep '97
      Pinky and Brain have a new companion, Larry, but their newest plan just doesn't seem to pan out.
    • 4. Where The Deer and The Mousealopes Play

      13 Sep '97
      In their latest plan, Pinky and Brain try to take over the steel mills in Pittsburgh, Pennsylvania by pretending to be a part of an endangered species called the Mousealopes.
    • 5. Brain Noir

      13 Sep '97
      It's 1946 and Brain's new plan gets interrupted when he and Pinky encounter Billie and Snowball.
    • 6. Brain's Bogie

      15 Sep '97
      Brain gets caught up in winning a golf tournament, even though it interferes with his new plan.
    • 7. Say What, Earth?

      15 Sep '97
      After the Earth gets the power of speech from his Silitronlinguifactor device, Brain comes up with a new plan.
    • 8. My Feldmans, My Friends

      16 Sep '97
      Brain tries to get a package meant for him back from his neighbor.
    • 9. All You Need Is Narf

      17 Sep '97
      Pinky becomes a guru during the 1960s.
    • 10. Pinky's Plan

      17 Sep '97
      It's Brain's birthday and Pinky plans a surprise party.
    • 11. This Old Mouse

      18 Sep '97
      After getting a glimpse of his future, Brain abandons his attempts to take over the world and gets a job as a ski instructor.
    • 12. Brain Storm

      19 Sep '97
      The mice are looking to control tornados, but a pest keeps getting in their way.
    • 13. A Meticulous Analysis Of History

      20 Sep '97
      Brain sings about past and present world leaders' failures.
    • 14. Funny, You Don't Look Rhennish

      20 Sep '97
      The mice need to get into a mine, but have to pretend to join a Amish-type society.
    • 15. The Pinky Protocol

      22 Sep '97
      Brain's latest plan is a conspiracy theory about why he is not ruling the world.
    • 16. Mice Don't Dance

      26 Sep '97
      Brain becomes a tap dancer with steam-powered legs in order to spread a subliminal morse code at the World's Fair.
    • 17. Brain Drained

      26 Sep '97
      Brain is out of ideas for taking over the world, so he tries to get some from writers.
    • 18. Brain Acres

      27 Sep '97
      Farmer Brain tries to grow an army of monster vegetables.
    • 19. Pinky And The Brainmaker

      29 Sep '97
      Brain creates a cloning machine and plans to clone himself in order to create the best Celtic dance troupe the world has ever seen.
    • 20. Calvin Brain

      29 Sep '97
      Brain masquerades as a fashion designer.
    • 21. Pinky Suavo

      04 Oct '97
      Brain plans to use the Personalitron to give him irresistible charisma, but it winds up going to Pinky.
    • 22. T.H.E.Y

      04 Oct '97
      The mice learn of a secret organization, T.H.E.Y. (comprised of world leaders), and try to get in.
    • 23. The Real Life

      10 Oct '97
      A house needed for Brain's latest plot becomes the set of a reality series about the people living there. So the mice become participants to get in.
    • 24. Brain's Way

      11 Oct '97
      To save his Las Vegas casino, Brain works as a lounge singer.
    • 25. A Pinky And The Brain Halloween

      19 Oct '97
      Mr. Itch offers Brain control of the world in exchange for his soul, but Brain refuses. In a shocking twist, Pinky sells his soul to make it happen and Brain soon decides to get his friend back.