Karthika was born to actress Radha and hotelier Rajasekharan Nair and is the niece of actress Ambika. She has two siblings, a brother and a sister. She did her studies in Podar International School in Mumbai and is now studying an international degree in Business from college affiliated to London School of Economics.

• கோ (2011)

  
• Dammu (2012)

  
• புறம்போக்கு என்கிற பொதுவுடமை (2015)

  
• கோ 2 (2016)

  
• జోష్ (2009)